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Posted by on Jul 10, 2012 in Science | 0 comments

What foods contain Nrf2?

One reader asked the question “What foods contain Nrf2?” Technically almost all food would contain Nrf2 as it is a fundamental cellular pathway.

What the real question should be is What foods will activate Nrf2 for me?

If you go to PubMed.gov which is the main database for biomedical and life sciences and search for Nrf2 you will find a couple of plant extracts which come up tops as being the most potent and effective Nrf2 activators in the published peer-reviewed scientific articles.

First is a compound call Sulforaphane. This is found in cruciferous vegetables such as cauliflower and broccoli.  However the highest concentrations are found in broccoli sprouts.  Population studies have linked higher intakes of cruciferous vegetables to lower rates of cancers.  And in the lab dish sulforaphane has been shown to be a potent inhibitor and cancer and tumor cells.

The other big hitter in the Nrf2 space is Curcumin which is the yellow pigment in the curry spice Tumeric.  This is thought to contribute to the lower rates of some cancers in Indians who eat a lot of tumeric in their traditional cooking.

One problem with curcumin is it doesn’t have a high bio-availability by itself.  Black pepper, and in particular a special extract called BioPerine, has been shown increase the absorption of curcumin in human clinical trials.

When Nrf2 is activated is causes the transcription of about 200 genes which encode a whole raft of protective enzymes and proteins.  In particular the glutathione enzymes which a responsible for the synthesis and catalysts to glutathione’s important functions in the body.

Now it’s great to have higher levels of these enzymes, but without more of the limiting building block of glutathione, which is cysteine, then activating Nrf2 by itself is going to have a limited beneficial effect.  It’s like upgrading the machinery in a factory, but not getting more of the raw ingredients to process.

The reason glutathione has hardly had any mainstream attention yet, despite it being your body’s master antioxidant and detoxifier, is because there hasn’t been effective ways to deliver cysteine intact into the cells.  It took one of the top medicinal chemists in the world to come up with the solution, which is a compound call RiboCeine.

The good news is now you can get RiboCeine, along with the potent nrf2 activators sulforaphane and cucrumin, along with 10 other potent ingredients, in a single convenient supplement call Cellgevity.

You’ll be reading more about Cellgevity when you click here!

 

Other people found this searching for:

  • what foods contain Nrf2 synergizers?

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